3 edition of Developmental immunotoxicology found in the catalog.
Includes bibliographical references and index.
|Statement||edited by Steven D. Holladay.|
|Contributions||Holladay, Steven D.|
|LC Classifications||RC582.17 .D484 2005, RC582.17 .D484 2005|
|The Physical Object|
|Pagination||364 p. :|
|Number of Pages||364|
|LC Control Number||2004054496|
Immunotoxicology (sometimes abbreviated as ITOX) is the study of toxicity affecting the immune system.. The toxin-induced immune dysfunction may take the form of immunosuppression, allergy, autoimmunity, increased susceptibility to cancer, or any number of inflammatory-based diseases or pathologies.. Examples of agents that can cause allergy-type . FDA says the guidance addresses issues related to evaluating immunotoxicity including immune suppression, modulation and stimulation and provides recommendations for carcinogenicity assessments, dermal sensitization, adjuvanted vaccine development and developmental and juvenile animal studies.
1 Immunotoxicology Testing: Past and Future Michael I. Luster G. Frank Gerberick 3. Part II Overview and Health-Risk Considerations. 2 Developmental Immunotoxicity (DIT): The Why, When, and How of DIT Testing Rodney R. Dietert Jamie DeWitt 17Price: $ The Second Edition of this highly regarded work provides a state-of-the-art review of developmental toxicology from basic science, clinical, epidemiological, and regulatory perspectives. This new edition highlights the latest approaches to understanding the mechanisms of developmental toxicity, testing pharmaceutical and environmental agents, and interpreting developmental .
28 Developmental Origins of Health and Disease Michael Cowley. Introduction Historical Perspective: Birth Weight and Early Life Nutrition in Adult Health The Effects of Environmental Chemicals on the Programming of Adult Health Biological Mechanisms Conclusions Suggested. Reading The third edition of the Toxicologist’s Pocket Handbook, like the first two editions, is a scaled-down version of the best-selling Handbook of provides the most frequently used toxicology reference information in a convenient pocket-sized book. The format remains the same as the earlier editions to allow basic reference information to be located quickly, with the .
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Developmental Immunotoxicology fills the void with overviews of immune system development in experimental animal and human models, and discusses the complex issues related to the evolution of developmental immunology and risk assessment.
Developmental Immunotoxicology fills the void with overviews of immune system development in experimental animal and human models, and discusses the complex issues related to the evolution of developmental immunology and risk Edition: 1st Edition. This is the first book to focuses on developmental immunotoxicology, it includes an overview of immune system development in animal models and humans and looks at issues related to the evolution of developmental immunotoxicology and risk assessment.
An important resource for toxicologists in pharmaceutical and biotechnology areas, this book discusses recently introduced systems for immunotoxicology testing and their applications. Immunotoxicology pharmaceutical safety assessments are important for streamlining the development process and reducing drug candidate : Hardcover.
Developmental immunotoxicology is defined as the study of the consequences of exposing the immune system to toxic agents during embryonic and fetal development. Thus, the qualifying term “developmental” refers directly to that period of embryonic and fetal differentiation and maturation of the immune system.
This textbook of developmental immunotoxicology was created to provide a nonexhaustive but reasonably extensive overview of available information concern- ing adverse postnatal consequences of perinatal immunotoxicant exposure.
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Continuing the tradition set by the first and second editions, each a bestseller in its own right, the third edition of Immunotoxicology and Immunopharmacology provides reviews of environmental agents, updated to reflect the latest information on how these agents influence immune system function and health.
Association on Immunotoxicology and the Pharmaceutical Industry (Immunotoxicology Task Force; March, ) •No “random screening”: problem-driven approach •Development of approaches using standard toxicology tests and species •More research in drug-induce hypersensitivity •Multidiscipline approach, involve clinicians, don’t.
Book Description. Continuing the tradition set by the first and second editions, each a bestseller in its own right, the third edition of Immunotoxicology and Immunopharmacology provides reviews of environmental agents, updated to reflect the latest information on how these agents influence immune system function and health.
Part XI: Bridging Immunotoxicology to Clinical Drug Development. Bridging Immunotoxicology to Clinical Drug Development (Ian Gourley and Jacques Descotes). Index. Reviews "I would recommend this book to toxicologists wishing to develop their knowledge in the specialised field of immunotoxicology.
The book provides extremely clear indication. "I would recommend this book to toxicologists wishing to develop their knowledge in the specialised field of immunotoxicology. The book provides extremely clear indication on the assessment of immunotoxicology and contains many recent references at the end of each chapter." (BTS Newsletter, Summer ).
Keywords biomarkers, developmental immunotoxicology, immune maturation, relative risk, windows of vulnerability Faith RE, Moore JA. Impairment of thymus-dependent immune functions by exposure of the developing immune system to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
Developmental immunotoxicity (DIT) has gained attention with the recognition that many chronic diseases of increasing incidence feature immune dysfunction as a component of the disease.
The maturing immune system represents a vulnerable target for toxicants as it progresses through a series of novel prenatal and perinatal events that are critical for later-life. Developmental immunotoxicity (DIT) appears to play a significant role in the current global epidemic of non-communicable diseases (NCDs) [1,2].
This review of DIT begins with the history of DIT placed in the context of the area of immunology known as immunotoxicology and charts the emergence of recent concepts concerning early developmental.
Immunotoxicology Immunotoxicology has excellent tools to simulate disease states and design models representing different conditions of immunological frailty and such models should also be applied for the study of nanomaterials. From: Adverse Effects of Engineered Nanomaterials (Second Edition), This review of DIT begins with the history of DIT placed in the context of the area of immunology known as immunotoxicology and charts the emergence of recent concepts concerning early developmental programming as it impacts later-life health.
The flow chart should be used first to determine whether immunotoxicity testing may be needed to support the safety of the device. Testing generally will be appropriate for new materials or when.
notoxicogenomics, developmental immunotoxicology, and the creation of adverse outcome pathways for immunotoxicity. The second speaker will address the particular data requirements under various laws and guidelines and their applicability to regulatory immunotoxicity.
Speaker number three will go into detail about specific required tests under.BIOLOGIC MARKERS IN IMMUNOTOXICOLOGY by immunotoxicology and a great selection of related books, art and collectibles available now at Passion for books. Sign On My Account Basket Developmental Immunotoxicology.
Holladay, Steven D. Published by CRC Press, U.S.A. () ISBN ISBN A workshop entitled ‘Developmental Immunotoxicology and Risk Assessment’ was held on 12–13 Junein Washington, DC. The workshop was organized jointly by the Immunotoxicology Technical Committ.